Eye Defects and Benlate

Researchers have discovere a rare and horrifying side effect that has caused nearly 1 in every 100,000 babies to be born without eyes. Additionally, this same side effect has caused 1 in 10,000 babies to be born with small eyes. Both of these conditions, known as anophthalmia and microphthalmia are the result of babies with genetic defects and babies being exposed to viral infections as well as environmental toxins, including Benlate.

Currently, at least ten children and their families have brought legal action against DuPont, the manufacturer of Benlate, claiming exposure to Benlate caused their eye defects; one in Florida, one in West Virginia, and eight in Delaware.

All, except for the Florida case, involve foreign plaintiffs. This is because fungicides are far more widely used in European countries than in the United States due to the damp climate. Fungus, and not insects, is the main crop killer there.

Additionally, in Britain, Benlate was available over the counter for use in the home. DuPont claimed that they removed Benlate from shelves in January of 1998 because it was becoming less effective, not because it was dangerous.

What causes these eye defects?

Normal development of the eye is an extremely complex process that relies on a precisely arranged sequence of developmental steps. During development, there are control genes that are switched on and off at particular times. The first few months of pregnancy is when a fetus develops its vital eye structures. However, after this there are still some refinements that occur. Failure of any of the early eye development stages may cause anophthalmia and/or microphthalmia. Later events in pregnancy such as infections or exposure to chemicals such as Benlate may also cause microphthalmia, but usually not anophthalmia. In most cases the cause of these problems is not known.

True anophthalmia occurs in around 1 in 100,000 births worldwide. Microphthalmia occurs in around 1 in 10,000 births. Around two thirds of these cases are believed to be genetic. The remaining are thought to be caused by environmental factors such as drugs, pesticides--such as Benlate, radiation, toxins, or viral causes. Some of the viruses that have been linked to these conditions are toxiplasmosis, rubella, and certain strains of the flu virus. Research into the cause or causes of these distressing conditions has intensified over the past few years.

What does science say about a link between eye defects in a fetus and Benlate exposure during pregnancy?

During animal testing, animals exposed to high doses of the pesticide had abnormal side effects including eye defects after birth. In 1997, DuPont funded a scientific study by an independent laboratory in Yorkshire. The internal report, details of which emerged in 2002, indicated that in rat studies a high proportion of benomyl, the active ingredient of Benlate, was drawn to the eyes.

According to research and reports, nearly one third of benomyl became concentrated in the eyes after only two hours; nearly two thirds pooled around the eyes after 24 hours. Nearly 80 percent of the main ingredient in Benlate, benomyl, had pooled around the eyes -- after only 10 days.

In 1991, 10 years before Benlate was removed from shelves, researchers at the University of California found that 40 percent of pregnant rats exposed to benomyl birthed rats with extreme defects of the eyes. When the dosage of benomyl was administered to rats given a protein-deficient diet, almost two out of three pregnant animals gave birth to babies without eyes.

The study was designed to show the impact of the Benlate chemical on those with a poor diet. Further, it has been pointed out that if the active substance of Benlate is inhaled or absorbed through the skin, it bypasses the liver and is therefore detoxified far more slowly. The chemical remains in a woman's system, and, for those who become pregnant, the effects on the fetus are severe.

Copyright (c) 2008 Katie Kelley

Article Source: http://www.articlesolve.com

Learn more about the eye defect and the exposure to Benlate at benlate.legalview.com/. Also visit www.LegalView.com and find the latest on other controversial legal issues including the Cipro side effects or the Levaquin risks.

Please Rate this Article

5 out of 54 out of 53 out of 52 out of 51 out of 5 

Not yet Rated